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Why feature free
applications on UBI's website? Like you, we prefer to only
pay for items when necessary. There are many free
applications that can do tasks that molecular biologists require.
We can save you time by putting these here. The reasons why
people graduate from free to commercial applications
that we market are:
- Scale - Most of the free applications are fine with a few
sequences, results, etc. but the work flow, storage requirements,
administrative needs, become untenable in many cases
after as few as 100 instances (sequences, results).
- Support - Free applications do not provide extensive help
or support resources. At some point, your time becomes
more valuable than what the free application is demanding.
- User Interface - Often free applications do not have a
sophisticated graphical user interface. This makes it
more difficult to learn and use them.
Applications (Free)
- BASE
is a comprehensive free web-based database solution for the
massive amounts of data generated by microarray analysis. It
is released under the GNU General Public License.
- European
Bioinformatics Institute (EBI) toolbox area provides a
comprehensive range of tools for the field of bioinformatics.
To view all tools
click here.
- NetPrimer
combines the latest primer design algorithms with a web-based
interface allowing the user to analyze primers over the
Internet.
- TIGR
The microarray software development team at TIGR (led by Dr.
John Quackenbush) has been very busy producing a software
suite entitled TM4.
Links
| Title |
Description |
| Bioinformatics Links Directory |
The Bioinformatics Links Directory features
curated links to molecular resources, tools and databases.
All of the resources are free or available for a nominal
fee. |
| BioSupplyNet |
Database of biotechnology
vendors. |
| CBHD Newsletter |
Canadian Bioinformatics Help Desk is an
excellent source for bioinformaticians whether in the
public or private domain. |
| Codon
Usage Tables |
Codon usage tabulated from
GenBank. |
| EndNote
and Reference Manager |
EndNote®, ProCite®,
Reference Manager® are software tools for publishing and
managing bibliographies on the Windows and Macintosh®
desktop. |
| Guide
to Sequence Analysis |
This guide will introduce the
reader to molecular sequence analysis. |
| Microarray
Analysis Methods |
Here is a very interesting
article from Modern Drug Discovery that reviews techniques
used to analyze microarray data. The techniques range from
unsupervised methods such as hierarchical clustering and
self-organized maps (SOMs) to supervised methods such as
the "nearest-neighbor" approach, classification
trees, support vector machines (SVMs), and neural
networks. Some of the supervised software packages that
are currently available include: MIT's GeneCluster,
Silicon Genetics' GeneSpring, and BioDiscovery's
GeneSight. Source: Modern
Drug Discovery |
| National
Center for Biotechnology Information |
Entrez, GenBank, homology
searches and more. |
| ORF
Finder |
Find open reading frames from
NCBI. |
| PA Subcellular Localization Web Server |
Believed to be the world's most accurate and
comprehensive predictor of protein sub-cellular
localization. |
| PNA
primer design guidelines |
Applied Biosystems guidelines
for sequence design of PNA oligomers. |
| Rebase |
The Restriction Enzyme
Database. |
| ScienceSlides |
ScienceSlides is a
PowerPoint-dedicated software for speakers and educators
in general biomedical fields. |
| STS
Finder |
Find a sequence tagged site
primer in your genomic sequence from NCBI. |
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